Leftover Pizza Chicken Sandwich

Featured in: Weeknight Dinners

This indulgent sandwich blends crispy leftover pizza slices used as bread with juicy shredded chicken, fresh peppery arugula, and melted mozzarella. Quick to prepare in just 20 minutes, it offers a satisfying twist on comfort food. Grill the layered sandwich in olive oil or butter until golden and melty. Variations include swapping greens or adding barbecue or pesto chicken for extra flavor. Serve warm, optionally with marinara for dipping, creating a perfect balance of textures and tastes.

Updated on Sun, 21 Dec 2025 11:58:00 GMT
Golden, crusty Leftover Pizza Chicken Sandwich, overflowing with melted cheese and tender chicken, ready to eat. Save to Pinterest
Golden, crusty Leftover Pizza Chicken Sandwich, overflowing with melted cheese and tender chicken, ready to eat. | shiftpan.com

I was staring into the fridge at three cold pizza slices and a container of shredded chicken when the idea hit me. What if the pizza wasn't just leftovers, but the solution itself? I grabbed two slices, flipped them crust-side down, and built what became my favorite way to reinvent yesterday's dinner. The first bite was crispy, gooey, and completely ridiculous in the best way. Now I actually look forward to leftover pizza nights.

The first time I made this for my roommate, she laughed out loud when I told her what I was grilling. Then she took a bite and went completely silent. She finished both halves without saying a word, then asked if we had more pizza in the fridge. That's when I knew this wasn't just a weird experiment anymore.

Ingredients

  • Leftover pizza slices: Any kind works, but try to pick slices with similar thickness so they press evenly and the cheese melts at the same rate.
  • Shredded chicken: Rotisserie chicken is perfect here because it's already seasoned and juicy, just pull it apart with your hands or two forks.
  • Fresh arugula: The peppery bite is key to balancing all the cheese and crust, don't skip it or the sandwich feels too heavy.
  • Shredded mozzarella: You need something that melts fast and stretches beautifully, a good Italian blend also works if that's what you have.
  • Mayonnaise: Optional, but a thin smear inside adds moisture and a subtle tang that really ties everything together.
  • Olive oil or butter: This is what crisps up the crust and gives you those golden edges that crunch when you bite in.
  • Black pepper and salt: Just a little pepper goes a long way with arugula, and taste before adding salt since pizza is usually salty enough on its own.

Instructions

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Prep the slices:
Lay two pizza slices crust-side down on your cutting board. If you're using mayo, spread a thin layer on the inside now, it keeps the chicken from drying out and adds a creamy richness.
Layer the chicken:
Divide the shredded chicken evenly between the two slices and season with black pepper. Taste a bit of the pizza first, if it's already salty you can skip the extra salt completely.
Add greens and cheese:
Pile on a generous handful of arugula, then shower it with shredded cheese. Don't be shy with the cheese, it's the glue that holds this whole thing together.
Close the sandwiches:
Top each with another pizza slice, crust-side up, and press down gently so everything settles in place.
Heat the skillet:
Warm your olive oil or butter in a nonstick skillet over medium heat until it shimmers. You want enough heat to crisp the crust but not so much that it burns before the cheese melts.
Grill until golden:
Carefully set the sandwiches in the skillet and press lightly with a spatula. Cook for 3 to 4 minutes per side, flipping gently, until the crust is golden and the cheese has melted into every corner.
Rest and serve:
Let the sandwiches sit for a minute after you pull them off the heat, then slice in half and serve immediately while everything is still hot and stretchy.
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There's something about biting into this sandwich that makes me smile every single time. It's messy and indulgent and completely unapologetic, the kind of food that reminds you cooking doesn't have to be fancy to be fun. I've served it to friends who thought I was joking, and watched them become converts halfway through their first sandwich.

Flavor Twists to Try

Once you nail the basic version, this sandwich becomes a playground for leftovers and flavor experiments. I've used barbecue chicken with red onion and cheddar, buffalo chicken with blue cheese crumbles and celery leaves, even pesto chicken with sun-dried tomatoes and provolone. Each version brings its own personality, but the method stays the same. If you have a flavor of chicken you love, it probably belongs in this sandwich.

Swaps and Substitutions

Arugula is my go-to, but baby spinach works if you want something milder, and fresh basil is incredible if your leftover pizza was margherita or anything tomato-heavy. For a vegetarian take, swap the chicken for roasted vegetables like zucchini, bell peppers, or eggplant. You can even use sautéed mushrooms with a little garlic, they bring a meaty texture without any actual meat. The key is to keep the filling fairly dry so the sandwich doesn't get soggy.

Serving Suggestions

This sandwich is rich and filling, so I like to serve it with something bright and simple on the side. A small green salad with lemon vinaigrette, a handful of pickles, or even just some cherry tomatoes cut in half with a sprinkle of salt. If you're feeling indulgent, warm up a little marinara or pizza sauce for dipping, it turns the whole thing into a deconstructed pizza experience that's way more fun to eat.

  • Try dipping it in ranch or garlic aioli for extra richness
  • Pair it with a cold beer or sparkling water with lemon
  • Cut into quarters and serve as a party appetizer, people go wild for it
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Close-up of a perfectly grilled Leftover Pizza Chicken Sandwich, showcasing layers of toppings and crisp pizza base. Save to Pinterest
Close-up of a perfectly grilled Leftover Pizza Chicken Sandwich, showcasing layers of toppings and crisp pizza base. | shiftpan.com

This sandwich taught me that the best recipes sometimes come from staring into the fridge and asking what if instead of what's supposed to go together. It's messy, it's fun, and it tastes like possibility.

Questions & Answers About This Recipe

Can I use different types of cheese in this sandwich?

Yes, mozzarella or an Italian cheese blend works well, but feel free to experiment with cheddar or provolone for varied flavors.

Is it necessary to add mayonnaise inside the sandwich?

Mayonnaise is optional; it adds moisture and richness but can be omitted for a lighter option.

What are good alternatives to arugula?

Baby spinach or fresh basil can substitute arugula, providing different flavor profiles and textures.

How do I achieve a crispy crust when grilling the sandwich?

Cook the sandwich in olive oil or softened butter on medium heat, pressing gently and flipping after 3–4 minutes to brown both sides evenly.

Can I make a vegetarian version of this sandwich?

Replace shredded chicken with roasted vegetables or a plant-based protein to keep it hearty without meat.

What pizza types work best for this sandwich?

Use leftover pizza slices of similar size and thickness; classic cheese or margherita pizzas are ideal bases.

Leftover Pizza Chicken Sandwich

A delicious sandwich featuring shredded chicken, arugula, cheese, and crispy pizza slices as bread.

Prep Time
10 min
Time to Cook
10 min
Total Duration
20 min
Recipe by Emma Miller


Skill Level Easy

Cuisine American/Italian Fusion

Serves 2 Portions

Dietary Info None specified

What You'll Need

Sandwich

01 4 cold leftover pizza slices, preferably similar size and thickness
02 1 cup cooked shredded chicken (rotisserie or leftover)
03 1 cup fresh arugula
04 1 cup shredded mozzarella or Italian cheese blend
05 2 tbsp mayonnaise (optional)
06 1 tbsp olive oil or softened butter for grilling

Seasonings

01 1/4 tsp freshly ground black pepper
02 Pinch of salt (optional, depending on pizza saltiness)

How to Make It

Step 01

Arrange Pizza Slices: Place two pizza slices crust-side down on a cutting board. Optionally spread a thin layer of mayonnaise on the interior side of each slice for moisture and flavor.

Step 02

Add Shredded Chicken and Seasoning: Evenly distribute the shredded chicken on each pizza slice. Season with freshly ground black pepper and a pinch of salt if needed.

Step 03

Add Arugula and Cheese: Layer a generous handful of fresh arugula atop the chicken, followed by an even sprinkle of shredded cheese.

Step 04

Assemble Sandwiches: Cover the toppings with the remaining two pizza slices, crust-side up, to complete two sandwiches.

Step 05

Preheat Skillet: Heat olive oil or softened butter in a large nonstick skillet over medium heat until shimmering.

Step 06

Grill Sandwiches: Place sandwiches in the skillet carefully. Press gently with a spatula and cook for 3 to 4 minutes per side, until cheese melts and the pizza crusts turn golden and crisp.

Step 07

Rest and Serve: Remove sandwiches from skillet, allow to rest for 1 minute, then slice in half and serve immediately.

What You'll Need

  • Large nonstick skillet or grill pan
  • Spatula
  • Knife and cutting board

Allergy Details

Review all items for allergies and speak to a healthcare expert with any concerns.
  • Contains wheat (pizza crust), dairy (cheese, possible pizza toppings), and possibly eggs (mayonnaise, certain pizzas)

Nutrition Details (per serving)

For reference only — always check with a nutrition or medical professional.
  • Caloric Value: 520
  • Fats: 24 g
  • Carbohydrates: 44 g
  • Proteins: 31 g